Actively Recruiting
Qingre Huatan Formula for the Prevention of Early Neurological Deterioration in Acute Ischemic Stroke
Led by Dongzhimen Hospital, Beijing · Updated on 2025-12-01
72
Participants Needed
1
Research Sites
71 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to assess the effectiveness and safety of Qingre Huatan formula versus placebo on preventing early neurological deterioration in patients with acute ischemic stroke within 48 hours after onset.
CONDITIONS
Official Title
Qingre Huatan Formula for the Prevention of Early Neurological Deterioration in Acute Ischemic Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Inpatients diagnosed with acute ischemic stroke
- Meet the criteria of traditional Chinese medicine phlegm-heat syndrome
- At high risk of early neurological deterioration (MRI shows new ischemic lesions with DWI-ASPECTS score 64 7, or presence of at least two risk factors of early neurological deterioration)
- Stroke onset within 48 hours prior to enrollment
- Aged 18 to 80 years, male or female
- Patient or representative has signed informed consent
You will not qualify if you...
- Received or planned thrombolysis or endovascular therapy after stroke onset
- Suspected secondary stroke caused by brain tumor, brain trauma, hemopathy, or similar conditions
- Dependent in daily activities before the current stroke (modified Rankin Scale score 652)
- Diseases causing motor dysfunction such as osteoarthritis
- Known severe liver or kidney dysfunction (elevated liver enzymes or creatinine beyond specified limits)
- Severe aphasia or mental illness affecting information collection and evaluation
- Pregnancy, potential pregnancy, or breastfeeding
- Currently participating in other clinical trials
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dongzhimen Hospital
Beijing, Beijing Municipality, China, 100700
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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