Actively Recruiting
Quadratus Lumborum Block to Improve Postoperative Pain Management After Laparoscopic Myomectomies: a Double-blinded and Prospective Randomized Clinical Trial.
Led by Joseph Findley MD · Updated on 2025-08-06
80
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of a quadratus lumborum (QL) block to reduce postoperative pain in women undergoing laparoscopic myomectomy for uterine fibroids. The study is a phase 4, double-blinded, randomized clinical trial comparing patients who receive the QL block with bupivacaine to those who receive a sham saline injection, alongside standard anesthesia and postoperative pain care. The goal is to determine if the QL block can improve pain management after surgery. Participants are randomly assigned to one of two groups: one group receives a QL block with a total of 60cc bupivacaine injected bilaterally into the quadratus lumborum muscles, while the other group receives a sham injection of 60cc saline in the same muscles. Both injections are given as part of the anesthesia during surgery. This study lasts up to 48 hours after hospital discharge for follow-up pain and satisfaction assessments. During the study, researchers will monitor the time from surgery until the first request for pain relief and count the total doses of rescue pain medication given within 24 hours. Pain levels will be measured using a visual analog scale (VAS) for up to 48 hours after discharge, along with patient satisfaction ratings on a scale of 1 to 10. Participants will be observed closely during this period to assess the impact of the QL block on postoperative pain control and overall experience.
CONDITIONS
Brief Title
QL Block in Laparoscopic Myomectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Presence of uterine fibroids requiring surgical excision with preservation of the uterus
- Willingness to comply with all study procedures and availability for the duration of the study
- Provision of signed and dated informed consent form
You will not qualify if you...
- Pre-existing diagnoses of anxiety or depression
- Pre-existing coagulopathies
- Pre-existing neuropathic or chronic pelvic pain
- Chronic opioid use
- Illiteracy due to inability to read and understand plain questionnaire
- Non-English speaking
- BMI >38
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 24 hours
Participants receive either a quadratus lumborum block with Bupivacaine or a sham injection with saline during laparoscopic myomectomy surgery to manage postoperative pain.
1 surgical visit (in-person)
Duration - Up to 48 hours after discharge
Participants are monitored for pain levels and satisfaction with pain management after discharge from the hospital.
1 follow-up visit (in-person or remote)
Trial Site Locations
Total: 1 location
1
University Hospitals Ahuja Medical Center
Beachwood, Ohio, United States, 44122
Actively Recruiting
Research Team
C
Catherine P Haering, BA
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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