Actively Recruiting

Phase Not Applicable
Age: 19Years +
All Genders
NCT05597683

Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy

Led by Gangnam Severance Hospital · Updated on 2024-08-15

50

Participants Needed

1

Research Sites

112 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to assess whether transmusculr quadratus lomborum block (QL block) can reduce postoperative pain after cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC). Patients will be randomly assigned to either QL block group or control group. Ultrasound-guided bilateral transmuscular quadratus lomborum block will be performed in QL block group using 0.375% ropivacaine. Multimodal analgesic regimen including acetaminophen, nonsteroidal antiinflammatory drugs (NSAIDs), and rescue opioids will be used in every patient. Primary outcome is opioid consumption for 24 hours after surgery. Secondary outcomes included pain scores, time to first rescue analgesics, quality of recovery score, length of hospital stay.

CONDITIONS

Official Title

Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients who are scheduled to undergo cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC)
Not Eligible

You will not qualify if you...

  • Allergy to local anesthetics or fentanyl
  • Chronic pain
  • Drug abuse
  • Patients who are unable to use patient-controlled analgesia
  • Skin infection at site for quadratus lomborum block
  • Pregnant or breastfeeding women
  • Patients who are unable to communicate

AI-Screening

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Trial Site Locations

Total: 1 location

1

Gangnam Severance Hospital

Seoul, South Korea

Actively Recruiting

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Research Team

S

SunKyung Park

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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