Actively Recruiting
Evaluation of Blood Flow in Radial, Ulnar, and Interdigital Arteries in Healthy Volunteers and Patients Using 3 Tesla MRI
Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-06-10
46
Participants Needed
1
Research Sites
43 weeks
Total Duration
On this page
Sponsors
C
Centre Hospitalier Universitaire, Amiens
Lead Sponsor
H
Hôpital Edouard Herriot
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying the blood flow in the arteries of the hand in both healthy individuals and patients with certain medical conditions, such as those who have had a radial forearm flap reconstruction or hand allotransplantation. This research aims to improve monitoring of vascular complications after transplantation using a special MRI technique developed to measure blood flow in small arteries of the hand. The study is led by the Centre Hospitalier Universitaire, Amiens, and focuses on comparing blood flow variations in different arterial trees under normal and pathological conditions. Participants will undergo MRI scans using a 3 Tesla Philips Research MRI device to capture detailed images of the radial, ulnar, and interdigital arterial trees. Additionally, a Doppler ultrasound procedure will be performed using traditional methods at the Vascular Medicine Department. The study includes groups of healthy volunteers, patients needing radial forearm flap reconstruction, and patients who have received hand allotransplantation. These procedures help evaluate vascular flow differences among these groups. During the study, participants will have their arterial blood flows measured on day 0, focusing on variations between healthy volunteers and patients. The research team will assess radial, ulnar, and interdigital artery flow patterns to understand vascular changes linked to transplantation or reconstruction. The study excludes individuals with MRI contraindications or specific arterial diseases except for those with hand transplants. Participation involves informed consent, and social security coverage is required. The trial aims to enhance vascular flow monitoring to better support transplant outcomes.
CONDITIONS
Brief Title
Qualitative and Quantitative Evaluation of Vascular Flows of Radial, Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult (18 years or older)
- Provided informed consent after receiving appropriate information
- Covered by social security insurance
- No contraindications to magnetic resonance imaging
- Healthy volunteer, patient needing radial forearm flap reconstruction, or patient having received hand allotransplantation
You will not qualify if you...
- Contraindication to MRI
- Pregnant or breastfeeding women
- Minors (under 18 years old)
- Persons under guardianship or deprived of liberty by judicial or administrative decision
- Persons with upper limb artery disease except hand transplant patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo MRI acquisitions and Doppler ultrasound procedures to evaluate blood flow in radial, ulnar, and interdigital arteries.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
CHU Amiens
Amiens, France, 80480
Actively Recruiting
Research Team
S
Sylvie testelin, Pr
B
Bernard Devauchelle, Pr
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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