Actively Recruiting
Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options - G-SCOPE (Glaucoma Surgery - Comparative Patient Evaluation)
Led by Hospices Civils de Lyon · Updated on 2026-03-16
132
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the impact of various glaucoma surgeries on patients' quality of life, beyond traditional clinical measures like eye pressure and medication use. This observational study focuses on adult patients with different types and stages of glaucoma who are undergoing specific surgical procedures. The goal is to better understand how surgery and postoperative care affect patients' daily lives and well-being. The study evaluates three types of glaucoma surgeries combined with mitomycin C: Preserflo MicroShunt implantation, trabeculectomy, and non-penetrating deep sclerectomy. Patients will be observed preoperatively and followed for at least six months after surgery. Quality of life will be assessed using the NEI-VFQ-25 questionnaire, which measures vision-related functioning and general health status. Participants will complete the NEI-VFQ-25 before surgery and again six months afterward. Researchers will collect clinical data on eye pressure, visual acuity, treatment burden, and visual field damage at three and six months post-surgery. The study will also monitor the impact of postoperative follow-up care on quality of life. The total involvement includes preoperative assessment and follow-up visits over six months to evaluate both subjective and objective outcomes.
CONDITIONS
Brief Title
Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged 18 years or older with an indication for glaucoma surgical treatment
- Eligible for Preserflo MicroShunt with mitomycin C, trabeculectomy with mitomycin C, or non-penetrating deep sclerectomy with mitomycin C
- Diagnosed with unilateral or bilateral glaucoma, open-angle or angle-closure, at early, moderate, or advanced stages
- Includes pseudoxexfoliative or pigmentary glaucoma
- Includes secondary glaucoma such as uveitic, steroid-induced, or traumatic glaucoma
- Provided written informed consent before participation
You will not qualify if you...
- Congenital glaucoma
- Refractory glaucoma with multiple previous surgeries
- Eye surgery within 6 months before joining the study
- Severe visual co-morbidities like age-related macular degeneration, severe diabetic retinopathy, or retinal degeneration
- Expected difficulty with follow-up due to poor compliance, travel, or prolonged absence
- Illiteracy, inability to speak French, or cognitive issues preventing study understanding
- Significant quality of life impairment from other progressive physical or neuropsychiatric illness
- Under curatorship or guardianship
- Pregnant women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of surgery and immediate recovery period
Participants undergo glaucoma surgery (sclerectomy + Mitomycin, PRESERFLO + Mitomycin, or trabeculectomy + Mitomycin) and receive immediate post-operative care.
1 surgical visit and immediate post-operative assessments
Duration - 6 months postoperatively
Participants have follow-up visits to assess recovery and quality of life after surgery using the NEI-VFQ-25 questionnaire and clinical evaluations.
Visits at Month 3 and Month 6
Trial Site Locations
Total: 1 location
1
Service d'Ophtalmologie, Hôpital de La Croix Rousse, Hospices Civils de Lyon
Lyon, France, 69317
Actively Recruiting
Research Team
V
Victor VERMOT-DESROCHES, MD
C
Christelle SZATANEK
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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