Actively Recruiting

Age: 18Years +
All Genders
NCT07303257

Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options

Led by Hospices Civils de Lyon · Updated on 2026-03-16

132

Participants Needed

1

Research Sites

74 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Glaucoma surgery currently relies on a wide therapeutic arsenal, ranging from conventional filtering surgeries to minimally invasive glaucoma surgery (MIGS). These techniques offer distinct efficacy and safety profiles, allowing tailored management across a broad spectrum of patients. Traditionally, surgical success has been evaluated using objective clinical outcomes, such as intraocular pressure (IOP) reduction and decreased reliance on topical treatments. However, the shift toward patient-centered medicine now requires consideration of the patient's perspective, including their subjective experience and the impact of treatment on quality of life. In this context, quality-of-life assessment has become a key component, promoting therapeutic alliance and patient adherence to care pathways. Despite its importance, few studies have evaluated and compared quality of life after glaucoma surgery using comparable surgical techniques. Furthermore, to our knowledge, no study has specifically assessed the independent effect of postoperative follow-up on quality of life after filtering surgery with a bleb. Given that postoperative management can be prolonged and demanding, it may significantly influence patients' perceptions of surgical outcomes and overall well-being. This study aims to address these gaps by providing a more comprehensive evaluation of the impact of glaucoma surgery beyond traditional clinical outcomes. It may represent a first step toward the development of a more appropriate assessment tool that incorporates the realities of postoperative follow-up and the specific experiences of patients undergoing filtering surgery. The study is based on the following hypotheses: filtering glaucoma surgery preserves patients' quality of life, with a stable NEI VFQ-25 score at six months postoperatively; postoperative quality of life may be influenced by the patient's postoperative care pathway; and quality-of-life scores remain correlated with objective clinical parameters, including intraocular pressure, visual acuity, medical treatment burden, and visual field damage.

CONDITIONS

Official Title

Quality of Life After Glaucoma Surgery: Evaluating the Patient Perspective Across Surgical Options

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged 218 years or older
  • Indicated for glaucoma surgical treatment
  • Eligible for Preserflo2 MicroShunt with mitomycin C, trabeculectomy with mitomycin C, or non-penetrating deep sclerectomy with mitomycin C
  • Unilateral or bilateral glaucoma, open-angle or angle-closure, at any stage
  • Diagnosis of pseudo exfoliative or pigmentary glaucoma
  • Secondary glaucoma types including uveitic, steroid-induced, or traumatic glaucoma
  • Written informed consent given before joining the study
Not Eligible

You will not qualify if you...

  • Congenital glaucoma
  • Refractory glaucoma with history of multiple previous surgeries
  • Eye surgery within 6 months before joining the study
  • Severe visual co-morbidities such as age-related macular degeneration, severe diabetic retinopathy, or retinal degeneration
  • Expected difficulty with follow-up like poor compliance or planned long absence
  • Illiteracy, inability to speak French, or cognitive impairment affecting understanding
  • Significant quality of life impairment due to progressive physical illness or neuropsychiatric disorder
  • Under curatorship or guardianship
  • Pregnant women

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Service d'Ophtalmologie, Hôpital de La Croix Rousse, Hospices Civils de Lyon

Lyon, France, 69317

Actively Recruiting

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Research Team

V

Victor VERMOT-DESROCHES, MD

CONTACT

C

Christelle SZATANEK

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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