Study of Quality of Life in Elderly Patients Aged 70 and Older with Low Grade Non-Hodgkin Lymphoma Receiving Immunotherapy, Immunochemotherapy, or Radiotherapy

What this Trial Is About

This research aims to understand how quality of life changes during the treatment of low-grade non-Hodgkin lymphoma in elderly patients aged 70 years and older. It focuses on identifying key factors at diagnosis and during treatment that affect quality of life. The study is observational and involves multiple centers, enrolling 150 patients with confirmed indolent non-Hodgkin lymphoma. Patients may receive various treatments including immunotherapy, immunochemotherapy at full or reduced doses, andor radiotherapy as part of their usual care. Before starting any treatment, all participants undergo a Comprehensive Geriatric Assessment. Quality of life is measured at three key points before treatment begins, at the end of treatment which can last from 1 to 6 months, and one year after starting therapy. Participants will be followed through routine clinical care, including baseline, post-treatment, and follow-up assessments. Quality of life is evaluated using detailed questionnaires EORTC-QLQ-C30 and FACT-Lym-LymS that cover general and lymphoma-specific symptoms. Researchers will also monitor survival outcomes and treatment safety over up to 30 months. This study involves no experimental treatments and focuses on observing real-world patient experiences.

Quality Of Life On Elderly Patients With Low Grade Non-Hodgkin Lymphoma