Actively Recruiting

Age: 18Years +
All Genders
NCT05393609

Quality of Life and Surgery in Diverticular Disease

Led by University of Aarhus · Updated on 2026-05-12

250

Participants Needed

1

Research Sites

292 weeks

Total Duration

On this page

Sponsors

U

University of Aarhus

Lead Sponsor

R

Randers Regional Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Diverticular disease is one of the most common diseases of the gastrointestinal tract in industrial countries. Prevalence and admission rate due to diverticular disease increases. Symptomatic patients usually present with acute uncomplicated or complicated diverticulitis. Recurrence rates of complicated diverticulitis are estimated to 10-30%. Recurrences, chronic complications or persisting pain, here collectively referred to as chronic diverticular disease, may be treated by elective sigmoidectomy. Currently, there is no specific criteria for elective surgery, but only a recommendation of a tailored approach depending on the patient's symptoms. It is well established that diverticular disease has a negative impact on quality of life (QoL). Elective laparoscopic sigmoidectomy may increase QoL. In this prospective study, we will prospectively examine QoL, patient-related outcomes and peri- and postoperative outcome of elective sigmoidectomy for chronic diverticular disease, and compare it to conservatively treated patients.

CONDITIONS

Official Title

Quality of Life and Surgery in Diverticular Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Referred to surgical clinic due to diverticular disease
  • Colonic diverticula verified by CT or endoscopy
Not Eligible

You will not qualify if you...

  • Previous colonic resection other than appendectomy
  • Previous or current colorectal cancer
  • Previous or current disseminated cancer
  • Inflammatory bowel disease
  • Psychiatric disorder influencing the ability to answer questionnaires
  • Inadequate Danish

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Randers Regional Hospital

Randers, Central Jutland, Denmark, 8930

Actively Recruiting

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Research Team

H

Helene R Dalby, MD

CONTACT

K

Katrine J Emmertsen, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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