Actively Recruiting
QuantiFERON-CMV Test in a Prediction for Colic Cytomegalovirus Reactivation During Ulcerative Colitis
Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2025-04-29
196
Participants Needed
2
Research Sites
350 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
CytoMegaloVirus (CMV) infection impairs evolution of Ulcerative Colitis (UC) leading to more severe and resistant to immunosuppressive therapies flare-up. CytoMegaloVirus (CMV) reactivation is assessed by the quantification of the CytoMegaloVirus (CMV) DeoxyriboNucleic Acid (DNA) load by real-time PCR (qPCR) in colonic biopsies; this assay is invasive and costly. The QuantiFERON-CytoMegaloVirus (QF-CMV) assay measures the immune response against CytoMegaloVirus (CMV) in a blood specimen.
CONDITIONS
Official Title
QuantiFERON-CMV Test in a Prediction for Colic Cytomegalovirus Reactivation During Ulcerative Colitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with seropositive for CytoMegaloVirus (CMV) (IgG+)
- Patient requiring hospitalization for flare of Ulcerative Colitis (UC) with Mayo score > 5 and an endoscopic subscore 65 2
- Social security affiliation
- Signed informed consent
You will not qualify if you...
- Wardship patient and curatorial patient
- Patient unable to understand or sign the protocol
- Colectomy total or partial
AI-Screening
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Trial Site Locations
Total: 2 locations
1
HCL-Hôpital Lyon Sud
Lyon, France
Actively Recruiting
2
Chu Saint-Etienne
Saint-Etienne, France
Actively Recruiting
Research Team
X
Xavier ROBLIN, MD PhD
CONTACT
S
Sylvie PILLET, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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