Actively Recruiting
Quantifying New Heart Muscle Cells
Led by Weill Medical College of Cornell University · Updated on 2025-07-28
30
Participants Needed
1
Research Sites
605 weeks
Total Duration
On this page
Sponsors
W
Weill Medical College of Cornell University
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Regenerative therapies could provide new ways of treating heart failure. Unlike many organs in the human body, such as the skin and the GI tract, the ability to regenerate heart muscle decreases after birth, but the precise timing of this decrease and how this decrease is altered in heart disease are uncertain. The investigators will use an innovative approach to quantify cellular heart regeneration in pediatric patients, an appropriate population for determining this decline as well as the potential for reactivating heart muscle regeneration. The study has now been registered on ClinicalTrials.gov, despite its initiation on July 23, 2015, as registration was not mandated at the original study site, the University of Pittsburgh Medical Center. However, following the transfer of the study to Weill Cornell Medicine, adherence to institutional requirements necessitated its registration on ClinicalTrials.gov.
CONDITIONS
Official Title
Quantifying New Heart Muscle Cells
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 30 days to 1 year undergoing scheduled elective cardiac surgery
- Patients with heart disease types, including Tetralogy of Fallot with Pulmonary Stenosis, likely requiring surgery with myocardial resection
- Diagnosis of heart disease with high likelihood of surgery involving routine myocardial tissue removal available for research
You will not qualify if you...
- Patients unlikely to have myocardial resection as part of their surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Weill Cornell Medicine
New York, New York, United States, 10065
Actively Recruiting
Research Team
R
Rashida Blackwood, BS, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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