Characterizing Uterine and Ovarian Tissue Stiffness Via Shear Wave Elastography in Non-Infertile, Fertile, and Infertile Women With Normal Anatomy Across the Menstrual Cycle: A Pilot Study

What this Trial Is About

Researchers are studying the elasticity of the female reproductive organs, including the uterus, cervix, and ovaries, by using shear wave elastography during different times of the menstrual cycle. The study aims to establish normal reference ranges for uterine and ovarian tissue stiffness. This knowledge may help in diagnosing and predicting outcomes for women seeking fertility treatments. The study involves measuring tissue stiffness with shear wave elastography, a device that uses ultrasound to assess elasticity in kilopascals. Participants are grouped into three categories: women with normal menstrual cycles and no prior pregnancy or infertility; women with normal cycles and at least one prior full-term vaginal delivery without infertility; and women with normal cycles and diagnosed primary infertility without uterine factor infertility. Each participant undergoes this assessment over approximately 3 to 4 months from enrollment. Participants will be monitored through shear wave elastography measurements to observe changes throughout their menstrual cycles. The primary outcome is the elastography parameters recorded within 3 to 4 months. This observational study includes women aged 18 to 45 years with normal uterine and ovarian anatomy. The study also involves detailed eligibility assessments to ensure participants meet criteria related to menstrual cycle regularity, anatomy, and reproductive history.

Quantifying Uterine Elastography in Menstruating Women