Actively Recruiting
A Quantitative, Cross-Sectional and Observational Study to Characterize Age-Related Structural Changes in Facial Skin of Chinese Women Using Line-Field Confocal Optical Coherence Tomography (LC-OCT)
Led by ChinaNorm · Updated on 2026-02-17
100
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a single-center, non-interventional, observational, cross-sectional clinical study designed to quantitatively and qualitatively characterize skin properties in a cohort of 100 Chinese female Subjects aged 20 to 70 years. The study involves no product application and poses minimal risk to participants. The primary objectives are to establish a comprehensive skin aging profile database, characterize skin color, aging signs, and biomechanical properties, and create a histomorphometric database for the development and validation of ordinal photographic scales for aging research. Data will be collected through questionnaires, clinical assessments (including LC-OCT imaging), standardized photography, and non-invasive biophysical measurements. All procedures will be conducted in accordance with the ethical principles originating from the Declaration of Helsinki, the International Council for Harmonisation Good Clinical Practice (ICH-GCP) guidelines, and the relevant laws and regulations of China (including the \*Measures for the Ethical Review of Biomedical Research Involving Human Subjects\*). All data will be anonymized and stored securely.
CONDITIONS
Official Title
A Quantitative, Cross-Sectional and Observational Study to Characterize Age-Related Structural Changes in Facial Skin of Chinese Women Using Line-Field Confocal Optical Coherence Tomography (LC-OCT)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chinese female aged between 20 and 70 years at consent
- Willing and able to provide written informed consent
- Fitzpatrick Skin Phototype II or III
- Willing to follow study procedures including removing facial makeup and avoiding intensive skincare on test areas for 3 days before the visit
You will not qualify if you...
- Pregnant, planning pregnancy, or breastfeeding
- Temporary tanning, sunburn, or significant redness on the face or measurement areas
- Facial piercings, tattoos, excessive fluff, or scarring interfering with imaging or measurements
- History of aesthetic or surgical facial procedures within the past 12 months
- Current diagnosis or visible signs of skin disease or systemic disease affecting the skin on face or measurement areas
- Use of systemic medications affecting skin physiology within past 3 months or for 6+ months in past 2 years
- Participation in another clinical study on face or arms within the past 1 month
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
HKRI Centre One
Shanghai, Shanghai Municipality, China, 200072
Actively Recruiting
Research Team
Y
Yanwen Jiang
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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