Actively Recruiting
Quantitative Sensory Testing and Central Sensitization in Endometriosis
Led by BC Women's Hospital & Health Centre · Updated on 2024-08-07
90
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
Sponsors
B
BC Women's Hospital & Health Centre
Lead Sponsor
U
University of British Columbia
Collaborating Sponsor
AI-Summary
What this Trial Is About
Endometriosis is a gynecologic condition where there is growth of endometrial-like tissue outside the uterus, leading to severe pelvic pain. Despite conventional treatment, many patients experience persistent pelvic pain due to central sensitization (CS), where the central nervous system amplifies pain signals. Quantitative Sensory Testing (QST) enables objective testing of CS. However, there are several patient-reported questionnaires that have shown promising potential as subjective proxies of CS. Therefore, in this study, our objective is to validate six patient-reported questionnaires as measures of CS by comparing them to each other and determining whether each questionnaire correlates with QST thresholds.
CONDITIONS
Official Title
Quantitative Sensory Testing and Central Sensitization in Endometriosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- New or re-referral appointment at the BC Women's Centre for Pelvic Pain and Endometriosis
- Consented to be contacted for future research in the centre data registry
- Surgically confirmed, imaging diagnosed, or clinically suspected endometriosis at appointment
- Female aged 19 to 49 years
- Willing and committed to completing six pain questionnaires
- Willing and committed to undergo Quantitative Sensory Testing (QST) if eligible
You will not qualify if you...
- Currently pregnant or breastfeeding
- Post-menopausal
- Does not speak English
- Diabetes or neurological disease causing neuropathic pain (QST specific)
- Previous laparotomy with large abdominal incision (QST specific)
- Physical trauma or scarring at QST test sites (deltoid muscle or thenar eminence)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
BC Women's Hospital + Health Centre
Vancouver, British Columbia, Canada, V6H 2N9
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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