Actively Recruiting
Quitting Matters Human Immunodeficiency Virus Hybrid Trial
Led by Wake Forest University Health Sciences · Updated on 2025-12-17
314
Participants Needed
1
Research Sites
171 weeks
Total Duration
On this page
Sponsors
W
Wake Forest University Health Sciences
Lead Sponsor
U
University at Buffalo
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to compare the advantages and disadvantages of two approaches for quitting smoking among people living with HIV (PWH). Participants will complete a 24- week (\~6-month) study where the Participants will be assigned to one of two smartphone apps to help with quitting smoking. Regardless of the group participants are assigned to, they will also receive a combination of nicotine replacement therapy (patches and gums) that have been shown to help people quit smoking. The main questions this study aims to answer are: Participants will complete 5 video call visits over about 6 months. Participants will install their assigned smoking cessation app onto their phone and will be asked to use the app for the duration of the study along with their provided Nicotine Replacement Therapy (NRT) products. During the study visits, participants will meet with study staff to complete questionnaires and interviews. Participants may be asked to provide breath and saliva samples to measure the level of carbon monoxide and nicotine.
CONDITIONS
Official Title
Quitting Matters Human Immunodeficiency Virus Hybrid Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Self-reported daily cigarette smoking over the past 30 days
- Self-reported HIV status
- Age 18 or older
- Desire to quit smoking
- Willing and medically eligible to use nicotine replacement therapy
- Currently receiving HIV care
- Currently owning an Android or iOS smartphone
You will not qualify if you...
- Current acute psychotic episode or unsafe to participate in the study
- Pregnant or intending to become pregnant in the next 6 months
- Currently receiving any pharmacological or behavioral intervention or counseling for smoking cessation
- Any medical condition or medication that could compromise safety as determined by study physicians
- Not able to fluently speak and write in English
- Hearing, comprehension, visual, speech, or motor limitations that prevent study participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Wake Forest University, Implementation Science
Winston-Salem, North Carolina, United States, 27101
Actively Recruiting
Research Team
R
Roger Vilardaga Vierra, Ph.D.
CONTACT
C
Clinical Studies Coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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