Actively Recruiting

Phase Not Applicable
Age: 18Years - 29Years
All Genders
Healthy Volunteers
NCT05958667

Quitxt Mobile Text Messaging Cessation Research Study

Led by The University of Texas Health Science Center at San Antonio · Updated on 2026-03-31

1200

Participants Needed

1

Research Sites

128 weeks

Total Duration

On this page

Sponsors

T

The University of Texas Health Science Center at San Antonio

Lead Sponsor

C

Cancer Prevention Research Institute of Texas

Collaborating Sponsor

AI-Summary

What this Trial Is About

The health benefits of smoking cessation by age 30 are much greater than cessation later in life, including gaining 10 years of life, compared with those who continue to smoke. The goal of the proposed study is to evaluate the effectiveness of the bilingual and culturally tailored Quitxt mobile cessation intervention. Quitxt provides interactive messages through texts or chat with visual and video content employing theory- and evidence-based techniques to prompt and sustain cessation. The study will recruit 1,200 Latino young adult smokers aged 18-29 who enroll and agree to make quit attempts, with half randomly assigned (like flipping a coin) to receive Quitxt and half to abbreviated text messages with smoking cessation-related content and referral to the Texas Department of State Health Services cessation program Yes Quit (which has diverse formats, but not explicitly tailored for young Latino adults in South Texas). Participants respond to baseline and follow-up assessments at one, three and six months after their enrollment, and those who report cessation will be asked to provide saliva samples to confirm they quit smoking. The sample size will be sufficient to detect expected higher cessation rates in those who are enrolled in Quitxt than those who are enrolled in Texas DSHS Yes Quit. The investigators will publish results in scientific journals, report them at scientific and community meetings, share them on social media, and publicize them widely. This study has the potential to advance public health by evaluating the effectiveness of a scalable, easily disseminated and adaptable intervention to help young adults, especially Latinos, quit smoking and reduce smoking-related cancer and chronic disease morbidity and mortality and their associated healthcare costs.

CONDITIONS

Official Title

Quitxt Mobile Text Messaging Cessation Research Study

Who Can Participate

Age: 18Years - 29Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Latino ethnicity
  • Aged 18 to 29 years
  • Smokes at least one cigarette per day on three or more days per week
  • Interested in quitting smoking
  • Willing to provide follow-up information
  • Not currently participating in another cessation program
  • Owns a cell phone or smartphone
  • Can send and receive text messages and access the Internet
  • Lives in the study area
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Not interested in quitting smoking
  • Unable to provide informed consent due to mental, emotional, or physical limitations
  • Does not own a cell phone with text and Internet capabilities
  • Unable to respond to text messages or access study materials (e.g., blind or deaf)
  • Plans to move away from the study area during the study period

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

The University of Texas Health Science Center at San Antonio

San Antonio, Texas, United States, 78229

Actively Recruiting

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Research Team

P

Patricia Chalela, DrPH

CONTACT

V

Vivian Cortez, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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