Actively Recruiting
R01.Aim 2.Study 1: IsoReach
Led by Shirley Ryan AbilityLab · Updated on 2025-01-09
56
Participants Needed
1
Research Sites
232 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To determine the effects of 3D isometric movement training in healthy participants and impaired participants due to a stroke.
CONDITIONS
Official Title
R01.Aim 2.Study 1: IsoReach
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Neurotypical participants must be 18 years old or older
- No history of stroke for neurotypical participants
- Ability to provide informed consent for neurotypical participants
- Stroke participants must be 18 years old or older
- Stroke participants must have chronic stroke (8+ months post-stroke)
- Stroke participants must have available medical records and imaging about lesion locations
- Stroke participants must have hemiparesis with primary motor cortex involvement
- Stroke participants must have some shoulder and elbow movement capability
You will not qualify if you...
- Neurotypical participants with severe medical problems including cardiovascular, orthopedic, or neurological conditions
- Neurotypical participants with medical problems affecting movement, range of motion, strength, or coordination of upper limbs
- Neurotypical participants with visual deficits affecting task performance (visual field deficits worse than 20/100, poor depth perception below specified thresholds)
- Neurotypical participants with blood pressure above 140/90 mmHg
- Neurotypical participants with blood oxygen less than 92%
- Stroke participants with bilateral paresis
- Stroke participants with aphasia, cognitive impairment, or affective dysfunction preventing task performance (based on Mini Mental State Examination scores adjusted for education)
- Stroke participants with visual deficits and hemispatial neglect preventing target seeing (assessed by visual field loss, visual extinction, and depth perception tests)
- Stroke participants with Modified Ashworth score of 4 at shoulder or elbow joints
- Stroke participants scoring below 15 on FMUE scale
- Stroke participants unable to provide informed consent
- Stroke participants with severe current medical problems
- Stroke participants with severe sensory deficit in the affected upper limb
- Stroke participants with diffuse/multiple lesion sites or multiple stroke events
- Stroke participants unable to maintain testing positions
- Stroke participants who received botulinum toxin injection to affected upper limb within previous 4 months
- Stroke participants currently in upper extremity rehabilitation therapy or research intervention
- Stroke participants with neurological, neuromuscular, or orthopedic diseases affecting the affected arm or hand
- Stroke participants with other neurological conditions such as Parkinson's or cerebral palsy
- Stroke participants with blood pressure above 140/90 mmHg
- Stroke participants with blood oxygen less than 92% on finger pulse oximetry testing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shirley Ryan AbilityLab
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
A
Arturo Ramirez
CONTACT
C
Courtney Celian, OTR/L
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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