Actively Recruiting

Phase Not Applicable
Age: 18Years - 99Years
All Genders
ID05425810

R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment

Led by North Carolina State University · Updated on 2025-05-20

3

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research focuses on lower limb amputees who rely on prosthetic legs to maintain an active and independent life. It aims to evaluate a new pressure sensing system designed to help prosthetists visually track pressure distribution on the residual limb, addressing challenges in creating well-fitted prosthetic sockets. The study tests the safety and effectiveness of this innovative sensing pad made with nanotube materials that change color based on pressure. Participants will undergo a series of procedures in three sets during 3-4 visits. The first set involves custom socket construction and fitting by certified prosthetists. The second set compares the new sensing pad's accuracy against a commercial sensor pad by mounting both on the residual limb and measuring pressure while walking. The third set tests how well the sensing pad helps prosthetists assess socket fit under different conditions using added small pads at specific limb locations. Throughout the study, participants will be monitored with high-resolution imaging and asked to complete a comfort survey about the sensing pad. Measurements include pressure distribution during walking and a discomfort chart after the final visit. Safety measures such as a fall prevention harness are available, and participants are encouraged to self-monitor and can end procedures early if needed. Total involvement includes multiple office visits and walking trials lasting about 4 hours in total.

CONDITIONS

Brief Title

R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Unilateral transtibial amputees
  • At least 1 year of experience using a prosthetic leg
  • Current prosthetic socket used for at least 6 months without significant skin issues or major modifications
  • Able to comfortably walk for 3 minutes without resting
  • Fibula length on residual limb greater than half of the unaffected side
Not Eligible

You will not qualify if you...

  • Cognitive or visual impairment affecting ability to give informed consent or follow instructions
  • Neuropathy observed on the residual limb
  • Pregnant female

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

3 to 4 visits to a local prosthetic company for socket construction and fitting

Device Testing

Duration - Several sessions over a few days

Participants will test the ENABLE sensing pad integrated into their prosthetic liner to measure pressure distribution during walking, compared to a commercial sensor pad. This includes mounting sensors and walking trials to stabilize measurements.

Multiple visits involving mounting sensors and walking trials with the ENABLE system

Socket Fit Assessment

Duration - Multiple trials within a session

Participants will undergo testing under five different socket fit conditions using small pads to change pressure distribution. They will complete walking trials to evaluate fit and comfort while pressure patterns are recorded and assessed by prosthetists.

3 to 4 visits with walking trials and evaluations under different fit conditions

Post-Testing Survey

Duration - 1 visit

After completing all experimental procedures, participants will fill out a survey to provide feedback on the comfort of the ENABLE system.

1 survey visit immediately following testing

Trial Site Locations

Total: 1 location

1

NC State University

Raleigh, North Carolina, United States, 27695

Actively Recruiting

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Research Team

M

Ming Liu, PhD

H

He Huang, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DEVICE_FEASIBILITY

Number of Arms

1

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Frequently Asked Questions

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