Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT06330844

Race-Based Stress and Cognitive Training for MCI

Led by Rosalind Franklin University of Medicine and Science · Updated on 2025-07-24

9

Participants Needed

1

Research Sites

158 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This a two phase project that aims to pilot a new adaptation (Phase 1) of Motivationally Enhanced Compensatory Cognitive Training for Mild Cognitive Impairment (ME-CCT; an originally VA-based cognitive rehabilitation manualized intervention for older adults with MCI, with a focus on the impact of stress on cognitive functioning; that integrates components from the Race Based Stress and Empowerment (RBSE) group for an increased focus on race-based stress and discrimination for racial minority older adults (i.e., RBSEF-CCT-MCI). In a pilot open trial, 75-150 participants will receive group-based intervention for 8 weeks, with 8-10 participants per group. Following the pilot study, the investigators will complete a randomized controlled trial (RCT) (Phase 2) to compare the efficacy of the RBSEF-CCT-MCI with the ME-CCT. In the RCT, 75-150 participants will be randomized into either 1) The active control group, who will complete the original, ME-CCT training program, or 2) The experimental group, who will complete the newly developed RBSE-CCT-MCI. Both research groups will complete the interventions for 8 weeks, with 8-10 participants per group. Hypothesis: Participation in this newly developed/updated intervention (i.e., RBSEF-CCT-MCI) will result in improvements in both (a) subjective and (b) objective cognitive functioning, and (c) self-reported mental health symptoms.

CONDITIONS

Official Title

Race-Based Stress and Cognitive Training for MCI

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Must be able to attend in-person sessions at Rosalind Franklin University
  • Must self-identify as Black/African American or as Black/African American along with another racial/ethnic group
  • May include participants who identify as Hispanic/Latine
  • Must be at least 65 years old
  • Must have mild cognitive impairment or self-reported cognitive difficulties
Not Eligible

You will not qualify if you...

  • Diagnosis of dementia or major neurocognitive disorder
  • Intellectual disability
  • Mild head injury or concussion within the last six months
  • History of moderate to severe traumatic brain injury
  • Cognitive assessment scores indicating dementia level (less than 2 standard deviations below mean on RBANS)
  • Not at least 65 years old or without mild cognitive impairment or cognitive difficulties

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Rosalind Franklin University of Medicine and Science

Chicago, Illinois, United States, 60064

Actively Recruiting

Loading map...

Research Team

R

Rachael L Ellison, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here