Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06627634

Radical Surgery for Advanced Gastric- or GEJ-cancer With Oligometastatic Dissmination to the Liver

Led by Aarhus University Hospital · Updated on 2024-10-04

20

Participants Needed

1

Research Sites

208 weeks

Total Duration

On this page

Sponsors

A

Aarhus University Hospital

Lead Sponsor

R

Rigshospitalet, Denmark

Collaborating Sponsor

AI-Summary

What this Trial Is About

Offering treatment with potential to cure for participants with no such offer in today's standard treatment options, by offering metastatectomia and standard treatment with intention to cure i.e., neoadjuvant chemotherapy and gastrectomy for participants with gastric- og gastroeusofageal junction cancer. Including 20 participants from all 4 centres in Denmark able to perform the surgical procedures in question. Endpoints: 2-year overall survival.

CONDITIONS

Official Title

Radical Surgery for Advanced Gastric- or GEJ-cancer With Oligometastatic Dissmination to the Liver

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18
  • Confirmed primary T1-T4N0-N3M1 adenocarcinoma of the stomach or gastroesophageal junction with maximum 30% liver involvement
  • Tumor that can be surgically removed based on imaging
  • Fit for surgery with ASA score less than or equal to III and WHO performance status 0-1
  • Eligible for systemic chemotherapy using the FLOT regimen
  • Provided informed consent
Not Eligible

You will not qualify if you...

  • Cancer that cannot be surgically removed
  • Tumor growing directly into nearby organs such as pancreas, colon, blood vessels, or bones
  • Other cancers diagnosed or treated within 2 years before joining, except non-aggressive skin cancers
  • Previous surgery that changed the normal anatomy of the upper digestive tract
  • Body mass index (BMI) less than or equal to 18
  • Unable to read or understand the consent form
  • Other serious illnesses or acute infections
  • Pregnant or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Aarhus Univercity hospital

Aarhus, Jylland, Denmark, 8200

Actively Recruiting

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Research Team

J

Julie Lykke Harbjerg, MD

CONTACT

D

Daniel Willy Kjaer, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Radical Surgery for Advanced Gastric- or GEJ-cancer With Oligometastatic Dissmination to the Liver | DecenTrialz