Actively Recruiting
Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
Led by International Spine Study Group Foundation · Updated on 2026-02-17
200
Participants Needed
16
Research Sites
573 weeks
Total Duration
On this page
Sponsors
I
International Spine Study Group Foundation
Lead Sponsor
D
DePuy Synthes
Collaborating Sponsor
AI-Summary
What this Trial Is About
Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.
CONDITIONS
Official Title
Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years old or older at time of treatment
- Diagnosis of cervical deformity meeting one or more of the following: C2-C7 sagittal kyphosis (Cobb > 15 degrees), T1S-CL > 35 degrees, segmental cervical kyphosis > 10 degrees between any 2 vertebrae between C2-T1 or > 15 degrees across any 3 vertebrae between C2-T1, cervical scoliosis > 10 degrees (Cobb angle within cervical spine), C2-C7 SVA > 4cm, McGregor's slope > 20 degrees or CBVA > 25 degrees
- Planned revision surgery for proximal junctional failure with anticipated upper instrumented vertebra in cervical spine and lower instrumented vertebra in thoracic or lumbar spine
- Plan for surgical correction of cervical deformity within next 6 months
- Willing to provide consent and complete study forms at baseline and follow-ups
- Upright AP/Lateral entire spine imaging (EOS or 36")
- Upright AP/Lateral cervical spine imaging if cervical spine not fully visible on entire spine films
- Flexion/extension lateral cervical spine imaging (exceptions allowed with documentation)
You will not qualify if you...
- Active spine tumor or infection
- Deformity caused by acute trauma
- Unwilling to provide consent or complete study forms
- Prisoner status
- Pregnant or immediate plans to become pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 16 locations
1
Shiley Center for Orthopaedic Research and Education at Scripps Clinic
La Jolla, California, United States, 92037
Actively Recruiting
2
University of California Davis, Department of Orthopedic Surgery
Sacramento, California, United States, 95817
Active, Not Recruiting
3
University of California-San Francisco Medical Center
San Francisco, California, United States, 94143
Actively Recruiting
4
Denver International Spine Center, Rocky Mountain Hospital for Children and Presbyterian St. Luke's Medical Center
Denver, Colorado, United States, 80128
Actively Recruiting
5
Rush University, Department of Neurosurgery
Chicago, Illinois, United States, 60612
Withdrawn
6
University of Kansas Medical Center, Department of Orthopedic Surgery
Kansas City, Kansas, United States, 66160
Actively Recruiting
7
Leatherman Spine Center, Department of Orthopedic Surgery
Louisville, Kentucky, United States, 40202
Actively Recruiting
8
Johns Hopkins University, Department of Neurological Surgery
Baltimore, Maryland, United States, 21224
Actively Recruiting
9
University of Michigan, Department of Neurosurgery
Ann Arbor, Michigan, United States, 48109
Completed
10
Hospital for Special Surgery, Department of Orthopedic Surgery
New York, New York, United States, 10003
Actively Recruiting
11
New York University, Department of Orthopedic Surgery
New York, New York, United States, 10003
Actively Recruiting
12
Columbia University Medical Center
New York, New York, United States, 10032
Actively Recruiting
13
Duke University Health System
Durham, North Carolina, United States, 27708
Actively Recruiting
14
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, United States, 15219
Actively Recruiting
15
Medical City Spine Hospital - Southwest Scoliosis Institute
Dallas, Texas, United States, 75243
Actively Recruiting
16
University of Virginia
Charlottesville, Virginia, United States, 22908
Actively Recruiting
Research Team
C
Christine Baldus, MS
CONTACT
R
Ray Pinteric
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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