Actively Recruiting
Radiomics-based Malnutrition for Cervical Cancer.
Led by Zhejiang Provincial People's Hospital · Updated on 2023-07-20
150
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Loss of skeletal muscle, is one of the most prevalent symptoms of malnutrition, and has been frequently reported as a negative factor in cancer patients at any disease stage. In this study, we are planning to firstly analyze the radiomics features of psoas extracted at the level of the third lumbar vertebra (L3) and then, develop a CT-based radiomics nomogram prediction model for predicting malnutrition based on their Patient-Generated Subjective Global Assessment (PG-SGA) scores in patients with International Federation of Gynecology and Obstetrics (FIGO, 2014 version) stage IB1-IIA2 cervical cancer (CC) who received postoperative radiotherapy/chemoradiotherapy (RT/CRT).
CONDITIONS
Official Title
Radiomics-based Malnutrition for Cervical Cancer.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who had pelvic lymphadenectomy and radical hysterectomy with pathological diagnosis of cervical cancer
- Patients with stage IB1-IIA2 cervical cancer according to the 2014 FIGO staging system
- Patients who received postoperative radiotherapy or chemoradiotherapy within one week after admission
- Patients with Eastern Cooperative Oncology Group performance status between 0 and 2
- Patients without prior treatments before radical surgery
- Patients with normal bone marrow function and recent blood tests meeting defined thresholds
- Patients without allergy to platinum-based chemotherapy drugs
- Patients willing to comply with nutritional therapy
- Signed informed consent
You will not qualify if you...
- Poor quality CT images or visible artifacts around the L3 psoas muscle
- Prior chemotherapy or radiation treatments
- Poor bone marrow, liver, or kidney function that would prevent tolerating therapy
- Participation in other clinical trials
- Pregnancy, breastfeeding, or not using birth control
- Major uncontrolled medical conditions such as active infections, serious heart conditions, psychiatric illness, or social issues limiting compliance
- History of another active cancer within the past five years
- Poor image quality or visible artifacts around the L3 psoas muscle
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
H
Hong'en Xu, M.D.
CONTACT
H
Huafeng Shou, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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