Actively Recruiting

All Genders
NCT06579768

Radiomics for Preoperative Jaw Cyst Differentiation

Led by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Updated on 2024-09-19

300

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

Sponsors

S

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Lead Sponsor

H

Hospital of Stomatology, Wuhan University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study focuses on jawbone cystic lesions, including odontogenic tumors like ameloblastoma and various cysts. Treatment approaches differ; ameloblastomas often require surgical excision due to potential recurrence and metastasis, while cystic lesions may be treated with curettage and marsupialization. Accurate preoperative diagnosis is crucial for optimal treatment outcomes, as inappropriate choices can lead to delayed treatment or overtreatment, affecting patient quality of life. Currently, there is no standard protocol for differential diagnosis, highlighting the need for a predictive diagnostic model. The study will be a multicenter, prospective machine learning research involving 300 patients across 12 centers. It aims to enhance a previously developed predictive model that integrates machine learning with CT radiomics. Patients will be grouped based on imaging modalities, with data processed uniformly to improve diagnostic predictions. Inclusion criteria ensure comprehensive preoperative data, while exclusion criteria eliminate incomplete or previously treated cases. The study seeks to optimize the model's performance and provide valuable clinical insights.

CONDITIONS

Official Title

Radiomics for Preoperative Jaw Cyst Differentiation

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • First-time visitors with no prior treatment interventions
  • Complete preoperative medical records, imaging examinations, and imaging data
  • Underwent maxillofacial CT examination before surgery with complete CT data and no artifact interference
  • Lesion size with longest diameter of at least 2 cm
  • Able to tolerate surgical treatment with specimens sent for routine pathological examination after surgery
Not Eligible

You will not qualify if you...

  • Incomplete medical records or missing examination and treatment operation records
  • Previous therapeutic operations at other hospitals with incomplete cure or recurrence
  • No preoperative CT examination or incomplete CT data with severe artifacts
  • Lesion specimens not submitted for examination during surgery
  • Unclear postoperative pathology reports or diagnosis other than odontogenic cysts or non-solid ameloblastoma

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sun Yat-sen Memorial Hospital,Sun Yat-sen University

Guangzhou, Guangdong, China, 510120

Actively Recruiting

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Research Team

Z

Zhiquan Huang

CONTACT

S

Songling Fang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Radiomics for Preoperative Jaw Cyst Differentiation | DecenTrialz