Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT05150145

Radiotherapy or Observation of Liver Metastases in Small Cell Lung Cancer

Led by Guizhou Medical University · Updated on 2025-06-26

66

Participants Needed

1

Research Sites

252 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this randomized study is to investigate local tumor control,survival outcomes and complications on patients of liver metastasis in small cell lung cancer.

CONDITIONS

Official Title

Radiotherapy or Observation of Liver Metastases in Small Cell Lung Cancer

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provided informed consent for radiation and medication before treatment
  • Aged between 18 and 70 years, any gender
  • Small cell lung cancer confirmed by histopathological or cytological examination
  • Presence of distant metastatic lesions, including liver metastasis
  • Physical status score (ECOG) between 0 and 2
  • Expected survival time longer than 3 months
  • Adequate bone marrow function: hemoglobin >90 g/L, platelets >100 x 10^9/L, neutrophils >1.5 x 10^9/L
  • Adequate liver function: ALT and AST less than 1.5 times upper limit of normal, total bilirubin less than 1.5 times upper limit
  • Adequate kidney function: serum creatinine below 1.5 times upper limit of normal, creatinine clearance over 55 mL/min
  • No prior thoracic radiotherapy or surgery
Not Eligible

You will not qualify if you...

  • History of mental illness
  • Presence of other malignancies
  • Active infections requiring intravenous antibiotic, antifungal, or antiviral treatments
  • Serious cardiovascular diseases including uncontrolled hypertension, unstable angina, recent myocardial infarction within 12 months, or severe arrhythmias
  • Poorly controlled diabetes making chemotherapy unsuitable
  • History of hepatitis or cirrhosis
  • Pregnancy or breastfeeding
  • Poor compliance with study requirements
  • Investigator judgment that participation is not appropriate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The affiliated hospital of Guizhou medical university

Guiyang, Guizhou, China, 550004

Actively Recruiting

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Research Team

S

Shengfa Su, PhD,MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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