Actively Recruiting
Radiotherapy to Patients With CA19-9-elevated Advanced Pancreatic Cancer
Led by Fudan University · Updated on 2025-08-07
210
Participants Needed
1
Research Sites
206 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the efficacy of chemotherapy plus radiotherapy to patients with CA19-9-elevated Advanced Pancreatic Cancer who are not refractory to chemotherapy.
CONDITIONS
Official Title
Radiotherapy to Patients With CA19-9-elevated Advanced Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to understand and willing to sign informed consent
- Age between 18 and 80 years
- ECOG performance status 0 to 2
- Confirmed advanced pancreatic adenocarcinoma by histology or cytology
- Not resistant to previous chemotherapy and no prior radiotherapy
- Locally advanced pancreatic cancer
- Baseline serum CA19-9 greater than 37 U/mL, with normal CA19-9 after chemotherapy
- At least one measurable tumor lesion per RECIST criteria
- Expected survival of at least 3 months
- Adequate organ function based on lab tests
- Agree to use contraception if of childbearing potential
You will not qualify if you...
- Pregnant or nursing women
- Primary pancreatic cancer
- Baseline serum CA19-9 37 U/mL or below
- Non-adenocarcinoma pancreatic cancer confirmed by pathology
- Digestive tract inflammation such as pancreatitis, cholecystitis, or cholangitis
- Severe or uncontrolled diseases affecting study compliance or results
- Renal insufficiency or dialysis
- Other serious illnesses affecting treatment safety
- Allergy to oxaliplatin or other chemotherapy drugs
- Unwilling or unable to follow study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shanghai Cancer Center
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
Y
Ying Yang, MD
CONTACT
G
Guopei Luo, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here