Comparing Knee Function and Range of Motion After Two Types of Navigated Total Knee Replacement Kinematic vs Mechanical Alignment

What this Trial Is About

Researchers are comparing two types of total knee replacement surgeries navigated kinematically aligned KA TKR and navigated mechanically aligned MA TKR, to see which results in better knee function and range of motion ROM. The study focuses on patients with degenerative osteoarthritis and evaluates functional outcomes and knee alignment over time. Participants will be randomly assigned to receive either KA TKR or MA TKR performed by experienced surgeons using navigation technology. KA TKR aims to restore natural knee joint lines, while MA TKR aligns the knee based on mechanical axes. Both groups will have patella resurfacing during surgery. The study includes preoperative and postoperative X-rays and standard follow-up visits up to one year. Participants will be assessed using the Knee Injury and Osteoarthritis Outcome Score KOOS at 12 months, along with secondary measures such as knee stability, Oxford Knee Score, SF-12, EQ5D, pain scores, operation time, and X-ray measurements. Follow-up visits occur at 6 weeks, 6 months, and 12 months, with adherence monitored through clinic visits and reminders. Safety is tracked as part of routine care, and participants may leave the study anytime without penalty.

A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR