Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT04246138

A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR

Led by Hull University Teaching Hospitals NHS Trust · Updated on 2026-03-18

100

Participants Needed

1

Research Sites

462 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The overall aim of the study is to compare navigated kinematically aligned total knee replacements (KA TKR) with navigated mechanically aligned TKR (MA TKR) in terms of function and ROM The objectives are therefore: 1. To compare the functional outcomes of KA TKR versus MA TKR performed using navigation technique 2. To compare ROM and alignment of knee in the two groups

CONDITIONS

Official Title

A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 90 years
  • Diagnosis of degenerative osteoarthritis
Not Eligible

You will not qualify if you...

  • Post traumatic arthritis
  • Varus or valgus deformity of more than 20 degrees
  • Flexion contracture of more than 20 degrees
  • Reduced ability to make decisions such as dementia or being a child
  • Orthopedic procedure to lower limbs within the last year
  • Neuromuscular or neurosensory deficiency
  • Inflammatory arthritis of the knee joint
  • Post-operative complications affecting outcome such as deep infection, fracture, or extensor mechanism dysfunction
  • Pregnancy
  • Participation in other clinical trials within last 6 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hull University teaching hospitals

Hull, East Yorkshire, United Kingdom, HU3 2JZ

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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A Randomised Control Trial Comparing Functional Outcomes for Navigated Kinematically Aligned TKR Versus Navigated Mechanically Aligned TKR | DecenTrialz