Actively Recruiting
A Randomised Controlled Trial of N-acetylcysteine for the Management of Alcohol Use Disorder
Led by University of Sydney · Updated on 2023-03-16
280
Participants Needed
3
Research Sites
193 weeks
Total Duration
On this page
Sponsors
U
University of Sydney
Lead Sponsor
M
Monash University
Collaborating Sponsor
AI-Summary
What this Trial Is About
To explore the effectiveness of n-acetylcysteine in improving treatment outcomes for alcohol use disorder in a double-blind randomised placebo-controlled trial.
CONDITIONS
Official Title
A Randomised Controlled Trial of N-acetylcysteine for the Management of Alcohol Use Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Alcohol Use Disorder according to the DSM-V criteria
- Desire to reduce or stop drinking
- Consumed at least 21 standard drinks per week or 2 heavy drinking days per week in the month prior to screening
- Adequate cognition and English skills to give valid consent and complete interviews
- Stable housing
- Willingness to provide written informed consent
You will not qualify if you...
- Pregnancy or lactation (women must use reliable contraception during the trial)
- Use of psychotropic medications other than stable-dose antidepressants
- Dependence on substances other than nicotine
- Clinically unstable medical or psychiatric disorders that prevent participation
- Concurrent use of selenium, vitamin D, or other antioxidants
- Use of any alcohol pharmacotherapy within the past month
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Drug Health Services, Royal Prince Alfred Hospital
Sydney, New South Wales, Australia, 2050
Actively Recruiting
2
Cornwall Street Medical Centre (UQ Health Care)
Annerley, Queensland, Australia, 4103
Not Yet Recruiting
3
Turning Point
Richmond, Victoria, Australia, 3121
Active, Not Recruiting
Research Team
K
Kirsten Morley, PhD
CONTACT
P
Paul Haber, MBBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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