Actively Recruiting
Randomized Assessment of TcMS for VT Storm
Led by University of Pennsylvania · Updated on 2026-04-21
60
Participants Needed
1
Research Sites
279 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Three-arm randomized clinical trial comparing two strategies of TcMS to sham stimulation in patients with VT storm. The hypothesis of the study is that TcMS will reduce the burden of VT in the 24 hours after randomization compared to sham stimulation and that TcMS with theta burst stimulation (TBS) will be more effective at reducing VT burden than low frequency TcMS.
CONDITIONS
Official Title
Randomized Assessment of TcMS for VT Storm
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 3 episodes of sustained ventricular tachycardia or appropriate ICD therapies within 24 hours despite using at least one antiarrhythmic drug
You will not qualify if you...
- Planned catheter ablation of ventricular tachycardia within the next 24 hours
- Pregnancy
- Contraindications to transcutaneous magnetic stimulation including implantable ventricular assist device, metal implants in head or neck (except the mouth), implanted medication pumps, cochlear implants, implanted brain stimulators, ocular implants, or history of malignancy in the neck
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
T
Timothy Markman
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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