Actively Recruiting
Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy
Led by University of California, San Diego · Updated on 2026-01-23
201
Participants Needed
3
Research Sites
134 weeks
Total Duration
On this page
Sponsors
U
University of California, San Diego
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate the effectiveness of a psychosocial intervention called iTEST for people with psychotic disorders that targets introspective accuracy, or the ability to accurately gauge ones abilities. iTEST combines daily cognitive training on a mobile device with coaching that addresses recovery goals. In this trial, we will randomize people to one of two interventions conditions, iTEST or a control condition that receives coaching and cognitive training that does not emphasize introspective accuracy. Both interventions will take place over 12 weeks and participants will be asked to complete assessments at baseline, 6 weeks, 12 weeks, and 24 weeks. The primary outcome of the study is community functioning. Participants will be from three metropolitan areas: San Diego, Dallas, or Miami.
CONDITIONS
Official Title
Randomized Clinical Trial of iTEST: A Blended Intervention Targeting Introspective Accuracy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntary informed consent and capacity to consent
- Age 18 to 65 years
- Diagnosed with schizophrenia or schizoaffective disorder
- Reading ability at or above 6th grade level
- Stable treatments with no hospitalizations or medication changes in past 2 months
- Have a clinician or close associate with monthly contact for informant input
- Have some functional impairment, not fully employed and financially independent
You will not qualify if you...
- Severe disorganization symptoms (score greater than 5 on P2-Disorganization item)
- Alcohol or substance dependence in the past 3 months
- Medical or psychiatric condition requiring care that prevents outpatient therapy
- Unable to see or use a smartphone adequately
AI-Screening
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Trial Site Locations
Total: 3 locations
1
UC San Diego
San Diego, California, United States, 92093
Actively Recruiting
2
University of Miami
Miami, Florida, United States, 33146
Actively Recruiting
3
University of Texas at Dallas
Dallas, Texas, United States, 75080
Actively Recruiting
Research Team
C
Colin A Depp, Ph.D.
CONTACT
N
Nikki Abaya, MA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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