Actively Recruiting
A Randomized Control Trial for Patient Reported Outcomes and Safety in Outpatient Thyroid Lobectomy
Led by M.D. Anderson Cancer Center · Updated on 2026-05-20
224
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to compare same-day discharge with the usual overnight stay after thyroid lobectomy, focusing on differences in patient preferences, safety outcomes, and economic and resource impacts. It particularly evaluates symptom severity using the MD Anderson Symptom Inventory - Thyroid (MDASI-Thyroid) at 24 hours and 2 weeks post-procedure, along with monitoring complications such as hematoma, emergency visits, readmissions, pain levels, and mortality. Morphine use during the two weeks after surgery is also assessed. Participants will complete surveys about their symptoms before surgery, one day after surgery, and two weeks later, mainly through electronic methods. At the pre-surgery visit, patients are randomly assigned to either same-day discharge or overnight hospital stay for observation. Monitoring continues for up to one month post-surgery, including possible virtual or in-person check-ins to discuss medication use and health needs. During the study, participants will complete symptom surveys and attend standard postoperative visits around two weeks after surgery. The research team tracks adverse events graded by national criteria over an average of one year. Follow-ups may include phone or in-person visits at one month to assess recovery and medication use. The total duration of involvement includes pre-surgery, immediate post-surgery, and one month of monitoring.
CONDITIONS
Brief Title
A Randomized Control Trial for Patient Reported Outcomes and Safety in Outpatient Thyroid Lobectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years of age or older
- Patients scheduled for initial partial or complete thyroid lobectomy
- English and non-English speaking patients are eligible
You will not qualify if you...
- Increased risk of bleeding that cannot be managed before surgery (e.g., aspirin, antiplatelet therapy, or anticoagulation not held 5 days before surgery, low platelet count)
- Pre-existing medical conditions or poor performance status requiring overnight hospital observation
- Living more than 50 miles from the hospital or unable to remain within 50 miles after surgery
- Living alone or unable to perform daily activities without a caregiver during the first 3 days after surgery
- Pregnant women
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for pre-surgery assessment
Duration - 1 day to overnight stay
Participants undergo thyroid lobectomy surgery and receive immediate post-operative care either with same-day discharge or an overnight hospital stay for observation.
Surgery day visit and hospital observation as assigned
Duration - Up to 1 month
Participants complete surveys about symptom severity at 24 hours and 2 weeks after surgery, and attend standard-of-care post-operative visits. Participants are monitored for up to 1 month after surgery, including possible phone or in-person contact to assess medication usage and health care needs.
Surveys at 24 hours and 2 weeks post-surgery, 1 standard post-operative visit at about 2 weeks, and possible phone or in-person contact at 1 month
Trial Site Locations
Total: 1 location
1
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
P
Paul Graham, M D
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
Frequently Asked Questions
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