Actively Recruiting
Randomized Controlled Clinical Trial of Hyperthermia and Hydrogen Peroxide 3% in the Treatment of Cutaneous Warts
Led by First Hospital of China Medical University · Updated on 2025-02-06
300
Participants Needed
2
Research Sites
212 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hyperthermia treatment (hyperthermia) refers to treating diseases with temperature (39-45 ° C) beyond normal body temperature,. It has been reported that local warming at 44 ° C is able to effectively mobilize the body's immunity and clear HPV infected lesions, such as condyloma acuminatum and verruca vulgaris, etc. Hydrogen peroxide (H2O2) is a commonly used disinfectant for skin debridement. It has been reported that high concentration of H2O2 (45% H2O2) is effective in the treatment of warts vulgaris, however, high concentration of H2O2 will cause more local pain, itching and burning sensation. 3% hydrogen peroxide is commonly used as skin debridement disinfectant. The purpose of the study is to evaluate the efficacy and safety of 44℃ hyperthermia combined with 3% hydrogen peroxide in treating verruca virus.
CONDITIONS
Official Title
Randomized Controlled Clinical Trial of Hyperthermia and Hydrogen Peroxide 3% in the Treatment of Cutaneous Warts
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged 16 to 65 years
- Clinical diagnosis of viral warts including common warts, plantar warts, or condyloma acuminatum
- Ability to understand and sign informed consent
You will not qualify if you...
- Presence of clinically atypical warts
- Immunocompromised status or history of HIV infection
- HPV vaccination within the past 6 months
- Use of immunomodulators or immunosuppressants within 4 months
- Use of systemic corticosteroids within 1 month
- Local therapies (laser, cryotherapy, retinoids) on or near warts within specified intervals
- History of cutaneous malignancies or current precancerous lesions
- Active dermatologic or systemic diseases such as psoriasis or eczema
- Skin conditions like sunburn that may increase study risks
- Any other medical or logistical reasons deemed exclusionary by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Guo Hao
Shenyang, Liaoning, China, 110001
Actively Recruiting
2
infrared hyperthermia device (Patent No: ZL 200820231952.4, Model: YY-WRY-V01, Liaoning Yanyang Medical Instrument Co., Ltd., China)
Shenyang, Liaoning, China, 110001
Actively Recruiting
Research Team
H
Hao Guo
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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