Actively Recruiting

Phase Not Applicable
Age: 20Years - 45Years
FEMALE
Healthy Volunteers
ID07246733

A Randomized Controlled Study on the Effect of MRJPs on Improving Ovarian Function and Endometrial Receptivity

Led by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · Updated on 2025-11-24

66

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the effects of royal jelly major proteins (MRJPs) delivered as rose tablet candies on ovarian function and endometrial receptivity in women aged 20 to 45 with normal menstrual cycles. The study will explore how MRJPs influence female reproductive health, focusing on their role in improving fertility factors such as hormone levels, ovarian reserve, and the uterine lining's ability to support embryo implantation. It also seeks to determine the safety and potential clinical value of MRJPs for reproductive medicine. Participants will be randomly assigned to one of two groups: one receiving oral MRJPs candy containing 70% MRJPs freeze-dried powder, and the other receiving a placebo candy mainly composed of whey protein powder. Both groups will take one tablet twice daily for one menstrual cycle. The MRJPs candy uses patented technologies to ensure quality and stability of the active ingredients. The placebo group allows comparison to evaluate the specific effects of MRJPs. Throughout the trial, researchers will monitor hormone levels, including anti-Müllerian hormone, and assess endometrial receptivity from enrollment through the one-month treatment period. Various tests and measurements will be conducted to track ovarian function and hormonal changes. The study is conducted with ethical oversight and scientific rigor to protect participants and ensure reliable results, with total participation lasting about one menstrual cycle plus screening and follow-up.

CONDITIONS

Brief Title

A Randomized Controlled Study on the Effect of MRJPs on Improving Ovarian Function and Endometrial Receptivity

Who Can Participate

Age: 20Years - 45Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Fertile women aged 20 to 45 years
  • Regular and normal menstrual cycles
Not Eligible

You will not qualify if you...

  • Allergic to royal jelly or its components
  • Suffering from severe chronic diseases or endocrine system disorders
  • Pregnant or breastfeeding
  • Undergoing hormone replacement therapy within the last month

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 1 menstrual cycle

Participants take oral MRJPs candy or placebo candy twice daily for 1 menstrual cycle to evaluate effects on ovarian function and endometrial receptivity.

1 baseline visit and 1 follow-up visit

Trial Site Locations

Total: 1 location

1

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Yiwu, Zhejiang, China, 322000

Actively Recruiting

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Research Team

X

Xiaolin Wu

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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