A Multi-center, Double-blinded, Randomized Controlled Study Comparing Modified Cup Anteversion vs Conventional Cup Anteversion Placement in Prevention of Postoperative Dislocation in Patients Undergoing Acetabular Tumor Resection and Reconstruction

What this Trial Is About

Researchers are studying patients with periacetabular tumors who undergo reconstruction surgery after tumor removal. The study aims to find out if using a modified angle for placing the acetabular cup during surgery reduces the risk of hip dislocation within one year compared to the conventional angle. This research is a multi-center, double-blinded, randomized controlled trial led by the Second Affiliated Hospital, School of Medicine, Zhejiang University. Participants are randomly assigned to receive either the modified anteversion angle placement or the conventional anteversion angle placement of the acetabular component during surgery. Both approaches use a 3D-printed osteotomy guide and prosthesis with pre-designed angles. Intraoperative X-ray fluoroscopy checks the cup angle to ensure it matches the predetermined criteria, adjusting it if necessary. During the one-year follow-up after surgery, researchers will monitor hip dislocation occurrences as the primary outcome. They will also assess function and recovery using MSTS and TESS scores and evaluate failure modes at 1 month, 3 months, 6 months, 9 months, and 1 year. The study includes detailed surgical evaluation and postoperative follow-up to measure safety and outcomes over this period.

A Randomized Controlled Study Evaluating Modified Cup Anteversion Placement in Prevention of Postoperative Dislocation in Patients Undergoing Acetabular Tumor Resection and Reconstruction