Actively Recruiting

Phase Not Applicable
Age: 12Years - 17Years
All Genders
Healthy Volunteers
NCT06526052

A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).

Led by Vanderbilt University · Updated on 2025-08-20

360

Participants Needed

3

Research Sites

156 weeks

Total Duration

On this page

Sponsors

V

Vanderbilt University

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this randomized clinical trial is to compare the effects of an online mindfulness program to an active supportive comparison condition and a no-intervention control group on reducing and preventing mood and anxiety symptoms in at-risk youth. Youth who are high on trait negative affect will be randomized to one of the three conditions. The primary outcomes of interest are reductions in momentary negative affect and internalizing problems in adolescents ages 12 to 17 years old. All participants will be evaluated prior to being randomized, after the 9-session intervention period, and at a 6-month follow-up. The first hypothesis is that the mindfulness intervention will predict decreases in stressor-reactive momentary negative affect and internalizing symptoms. The second hypothesis is that changes in momentary negative affect will partially account for the effects of the mindfulness intervention on internalizing symptoms.

CONDITIONS

Official Title

A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).

Who Can Participate

Age: 12Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 12, 13, 14, 15, 16, 17
  • Parental consent provided
  • Participant assent obtained
  • Live in Illinois, California, or Tennessee
Not Eligible

You will not qualify if you...

  • Current diagnosis of anxiety or depressive disorder with significant clinical impairment
  • Current alcohol or substance use disorder
  • Current serious suicidal ideation or behavior
  • Lifetime diagnosis of bipolar disorder, schizophrenia, autism, conduct disorder, or developmental delay
  • Reading level below 4th grade
  • Not English speaking at a level that would allow participation in the intervention and assessments

AI-Screening

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Trial Site Locations

Total: 3 locations

1

University of California, Los Angeles

Los Angeles, California, United States, 90095

Actively Recruiting

2

Northwestern University

Evanston, Illinois, United States, 60208

Actively Recruiting

3

Vanderbilt University

Nashville, Tennessee, United States, 37203-5721

Actively Recruiting

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Research Team

J

Judith A Garber, PhD

CONTACT

S

Steven D Hollon, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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