Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07164885

RAPART in Locally Advanced Non-small Cell Lung Cancer Patients

Led by Capital Medical University · Updated on 2025-12-02

911

Participants Needed

1

Research Sites

149 weeks

Total Duration

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AI-Summary

What this Trial Is About

This is a Phase II/III randomized clinical trial of Radiosensitivity-Assisted Personalized Adaptive Radiotherapy Technology (RAPART) in locally advanced non-small cell lung cancer patients. The main objective is to test the overall improvement of overall survival (OS), progression free survival (PFS), and local progression free survival (LPFS) of unresectable stage III NSCLC under standard and non-standard mixed treatment conditions compared to conventional 60Gy radiotherapy.

CONDITIONS

Official Title

RAPART in Locally Advanced Non-small Cell Lung Cancer Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged over 18 years
  • Pathologically confirmed non-small cell lung cancer
  • All unresectable stage III non-small cell lung cancer, including stage changes after multidisciplinary team evaluation or treatment
  • ECOG performance status between 0 and 2
  • Participants may be treatment-naive or have received surgery, chemotherapy, immunotherapy, or targeted therapy
Not Eligible

You will not qualify if you...

  • Prisoners unable to undergo close clinical follow-up
  • Participants with contraindications to radiation therapy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Hong Kong Shenzhen Hospital

Shenzhen, Guangdong, China, 518000

Actively Recruiting

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Research Team

F

Feng-Ming (Spring) Kong

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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