Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06189976

Rapid Atrial Pacing After TAVI to Predict Pacemaker Implantation

Led by National and Kapodistrian University of Athens · Updated on 2024-12-12

400

Participants Needed

2

Research Sites

95 weeks

Total Duration

On this page

Sponsors

N

National and Kapodistrian University of Athens

Lead Sponsor

C

Centre Hospitalier Universitaire Saint Pierre

Collaborating Sponsor

AI-Summary

What this Trial Is About

Despite Transcatheter aortic valve implantation (TAVI) evolution regarding techniques, equipment and experience, the need for permanent pacemaker implantation (PPI) post-TAVI remains an important drawback. The electrophysiology testing to stratify the risk or necessity of PPI post-TAVI is endorsed by the up-to-date guidelines and consensus documents and it is a valuable cut-off based method. Part of the answer is maybe hidden in the easy and applicable testing of the atrioventricular conduction system through rapid atrial pacing (RAP) with a common temporary pacemaker lead. This trial is designed to investigate the role and value of RAP after TAVI as a predictor of the necessity of new PPI.

CONDITIONS

Official Title

Rapid Atrial Pacing After TAVI to Predict Pacemaker Implantation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years old or older
  • Patient understands the trial purpose, risks, and benefits and is willing to participate in all follow-up parts
  • Patient has given written consent to join the trial
  • Patients undergoing TAVI for severe aortic stenosis
  • Patient is in sinus rhythm
  • Patients planned for TAVI with temporary pacemaker electrode placement
Not Eligible

You will not qualify if you...

  • Ongoing infection, including active endocarditis
  • Implanted permanent pacemaker or implantable cardioverter/defibrillator
  • Persistent second or third degree atrioventricular block after TAVI
  • Heart rhythm other than sinus after TAVI
  • Second or third degree atrioventricular block identified on pre-TAVI ECG
  • Participation in another conflicting clinical study
  • Unable to comply with follow-up requirements as judged by investigators
  • Pregnant or breastfeeding females or females planning pregnancy during the study

AI-Screening

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Trial Site Locations

Total: 2 locations

1

CHU Saint-Pierre

Brussels, Belgium, 1000

Actively Recruiting

2

Hippocration Hospital

Athens, Attica, Greece, 11527

Actively Recruiting

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Research Team

L

Leonidas Koliastasis, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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