Actively Recruiting
Rapid Increase of Lipid Lowering Therapy to Prevent Repeat Cardiovascular Events in Adults with Coronary Artery Disease
Led by Chinese University of Hong Kong · Updated on 2025-12-31
1000
Participants Needed
1
Research Sites
25 weeks
Total Duration
AI-Summary
What this Trial Is About
This research aims to evaluate the impact of frequent monitoring and adjustment of lipid-lowering therapy LLT to achieve target low-density lipoprotein cholesterol LDL-C levels in patients with hyperlipidemia and cardiovascular disease. The study focuses on patients with acute or chronic coronary syndrome due to atherosclerotic coronary artery disease. Despite guidelines recommending aggressive LDL-C lowering primarily with statins, many patients do not reach their LDL-C goals due to factors like non-adherence and limited use of additional therapies. Participants include patients diagnosed with acute or chronic coronary syndrome caused by atherosclerosis. The study observes how frequent LDL-C testing and timely changes in LLT at a specialist clinic affect LDL-C control. There is no interventional treatment assigned rather, the study collects data on LDL-C levels and therapy adjustments over time to assess current clinical practice strategies. During the study, LDL-C levels will be measured at baseline and at weeks 8, 26, and 52. Researchers will also monitor participants achievement of LDL-C targets, adherence to lipid-lowering therapy, tolerability, and any major cardiovascular events. Quality of life will be assessed using the 12-Item Short Form Survey at the same time points. The study is observational, with follow-up lasting up to one year to gather comprehensive data on lipid management and cardiovascular outcomes.
CONDITIONS
Brief Title
Rapid Escalation of LipiD Lowering Therapy to Reduce RecUrrent Cardiovascular Event
Research Team
G
Guangming Tan
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