Actively Recruiting
Rapid Escalation of LipiD Lowering Therapy to Reduce RecUrrent Cardiovascular Event
Led by Chinese University of Hong Kong · Updated on 2025-12-31
1000
Participants Needed
1
Research Sites
339 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hyperlipidaemia especially elevation of low-density lipoprotein cholesterol (LDL-C) is known to be the main contributor to the development of atherosclerotic cardiovascular disease (ASCVD). Lowering LDL-C have been shown to reduce the risk of ASCVD2,3. Both the American Heart Association (AHA) and the European Society of Cardiology (ESC) advocated aggressive LDL-C target with statin being the first-line lipid-lowering therapy (LLT). However, a significant portion of patients did not attain their LDL-C goal in our locality. Statin no adherence, low uptake of adjuvant non-statin LLT, and therapeutic inertia are few potential causes for not achieving the LDL-C target. ESC recommends repeating blood test in 6-8 weeks after addition or alternation of LLT, but this recommendation was not routinely followed in current local practice due to resources constrain. This registry therefore aims to investigate the strategy of frequent monitoring of LDL-C and titration of LLT in achieving LDL-C treatment target at a dedicated specialist clinic.
CONDITIONS
Official Title
Rapid Escalation of LipiD Lowering Therapy to Reduce RecUrrent Cardiovascular Event
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age >18
- Diagnosis of acute coronary syndrome due to atherosclerotic coronary artery disease
- Diagnosis of chronic coronary syndrome due to atherosclerotic coronary artery disease
You will not qualify if you...
- Unable to provide valid consent by the patient or legal guardian
- Acute coronary syndrome caused by conditions other than atherosclerotic coronary artery disease
- Psychiatric or severe neurological disorder, cirrhosis, or active malignancy with life expectancy less than 6 months
AI-Screening
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Trial Site Locations
Total: 1 location
1
Prince of Wales Hospital
Shatin, New Terrritories, Hong Kong, 999077
Actively Recruiting
Research Team
G
Guangming Tan
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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