Testing the PA-100-AST Rapid Urine Test for Diagnosing Bladder Infections in Adult Women Comparison with Standard Lab Culture in General Practice

What this Trial Is About

This research focuses on adult women who visit their general practitioner with symptoms suggesting a bladder infection, such as burning during urination, lower abdominal pain, and frequent or urgent urination. The study aims to evaluate the accuracy of a new point-of-care urine test system called PA-100-AST from Sysmex, comparing it to the traditional laboratory urine culture test. This observational study is conducted in general practice settings to see how well the PA-100-AST performs for diagnosing uncomplicated urinary tract infections in women. The PA-100-AST system rapidly detects bacteria in urine and reports antibiotic susceptibility for common antibiotics used to treat urinary tract infections. It identifies bacterial groups but does not specify exact bacterial species. Urine samples are tested immediately after collection with the PA-100-AST, and additional samples are sent to labs for standard culture tests. The study involves adult women suspected of uncomplicated UTIs visiting several general practices, with all testing done under routine conditions. Participants provide urine samples and complete a questionnaire at their initial visit. Researchers collect clinical data, dipstick test results, and antibiotic susceptibility information. The main outcome measures include the tests sensitivity, specificity, predictive values, and likelihood ratios compared to the lab culture. The study also explores agreement between the PA-100-AST and lab susceptibility results. Participation involves routine consultations, and results help assess the new tests usefulness in general practice.

Rapid Point-of-care Bacteriuria and Microbial Susceptibility for Women With Suspected Uncomplicated Urinary Tract Infections: Diagnostic Accuracy in General Practice.