Actively Recruiting
RAPID-POP a Randomized Controlled Trial
Led by National Institute of Cardiovascular Diseases, Pakistan · Updated on 2024-05-29
400
Participants Needed
1
Research Sites
24 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Efficacy of the Pressure Optimization Protocol (POP) versus Conventional Stent Deployment Strategy during Primary PCI: An Open Label Randomized Clinical Trial The investigators will compare conventional rapid stent inflation/deflation during primary PCI with higher pressure and prolonged duration of stent deployment Study Hypothesis: The POP in stent deployment is superior to the conventional stent deployment approach with a significantly higher achievement of the TIMI III flow, significantly lesser occurrence of slow flow/no-reflow, and significantly higher rate of ST-Segment resolution during primary PCI.
CONDITIONS
Official Title
RAPID-POP a Randomized Controlled Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years and above.
- Patients undergoing primary percutaneous coronary intervention (PCI) with stent implantation.
- Presence of significant coronary artery stenosis (greater than 70% diameter reduction) confirmed by angiography.
You will not qualify if you...
- Patients with Killip class IV.
- Patients with significant comorbidities such as end-stage renal disease or advanced liver disease which may interfere with the procedure or follow-up.
- Prior history of coronary artery bypass grafting (CABG).
- Refusal to give consent for study participation or procedure.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National institute of cardiovascular diseases
Karachi, Sindh, Pakistan, 75510
Actively Recruiting
Research Team
A
Abdul Hakeem, professor
CONTACT
S
Shakir Zada, fellow
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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