Actively Recruiting

Age: 18Years +
All Genders
NCT06597383

The RApid Switch From 1st Generation Somatostatin Analogues to PaSireOtiDe In Acromegaly

Led by IRCCS San Raffaele · Updated on 2024-09-19

100

Participants Needed

1

Research Sites

49 weeks

Total Duration

On this page

Sponsors

I

IRCCS San Raffaele

Lead Sponsor

U

University of Turin, Italy

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is an observational, retrospective, national multicenter study aimed to evaluate the impact and efficacy of Time To Switch (TTS) from first-line to second-line medical therapy in Acromegaly.

CONDITIONS

Official Title

The RApid Switch From 1st Generation Somatostatin Analogues to PaSireOtiDe In Acromegaly

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult men and women aged 18 years or older with acromegaly
  • Patients inadequately controlled with first generation somatostatin analogues (GH ≥1 µg/L and IGF-1 >1.3×ULN)
  • Patients who switched to second line medical treatment (Pasireotide; Pegvisomant only; combination Pegvisomant + 1st generation SSA) after first-line treatment
  • At least 12 months of follow-up during second-line therapy
  • Signed informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • Pregnant or breastfeeding women
  • Patients unable to understand or sign the informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Andrea Giustina

Milan, Italy, 20132

Actively Recruiting

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Research Team

L

Luigi Di Filippo, medical doctor

CONTACT

G

Gabriela Felipe, clinical research nurse

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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The RApid Switch From 1st Generation Somatostatin Analogues to PaSireOtiDe In Acromegaly | DecenTrialz