Actively Recruiting
Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation
Led by Florida State University · Updated on 2025-05-14
132
Participants Needed
1
Research Sites
216 weeks
Total Duration
On this page
Sponsors
F
Florida State University
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will test the clinical efficacy of an accelerated TMS (accel-TMS) protocol that rapidly addresses PTSD symptoms with 1 week (25 sessions over 5 days) of condensed treatment.
CONDITIONS
Official Title
Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults age 18 years to 65 years old
- Meets DSM-5 criteria for PTSD with a PCL-5 score > 33
- No changes in psychotropic medication or supportive psychotherapy for 1 month prior to initial visit
- Clinically appropriate to maintain stable treatment regimen during the trial
- Able to give informed written consent and comply with study procedures for the entire study
You will not qualify if you...
- Medical contraindications for neuromodulation such as ferrous metal in head, seizure disorder, brain tumor, stroke, aneurysm, multiple sclerosis
- Active substance use disorder in last 3 months or current substance use causing significant impairment
- Dementia or cognitive disorder preventing engagement in treatment
- History or diagnosis of Schizophrenia, Schizoaffective Disorder, Delusional Disorder, or other psychotic illness
- Suicidal risk that precludes safe participation
- OCD cannot be the primary disorder but symptoms allowed
- Inability to stop medications that lower seizure threshold
- Current, planned, or suspected pregnancy
- Unstable medical conditions precluding safe TMS participation
- Severe Traumatic Brain Injury
- Non-English speakers excluded due to need for rapid communication
- Significant ongoing litigation or claims impacting research
- Prior active TMS of dl-PFC or dm-PFC or electroconvulsive therapy (ECT)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Florida State University
Tallahassee, Florida, United States, 32306
Actively Recruiting
Research Team
I
Isabelle M Taylor, MA
CONTACT
K
Kevin A Johnson, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
5
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here