Study Comparing Joint Infection Rates 90 Days After Hip Replacement Surgery Using Next Science No-Rinse Solution Versus Standard Saline Irrigation

What this Trial Is About

Researchers are evaluating the 90-day rate of joint infections in adults undergoing primary hip replacement surgery. This trial compares the use of Next Science No-Rinse Solution NS to the standard saline irrigation SOC to see which method better reduces post-operative joint infections. The study is a randomized, controlled clinical trial conducted at a single site with two parallel groups. Participants will be randomly assigned to one of two groups the experimental group, where the surgical site is irrigated with NS prior to closure and suctioned at the end of treatment, or the control group, where saline irrigation is used. This treatment is applied during surgery just before closing the surgical site. Throughout the study, participants will be monitored for joint infections up to 90 days after surgery. Researchers will also assess any changes in heart rhythm QT prolongation within 24 hours from irrigation to closure. Participants must be available for all scheduled visits and follow study procedures, including transportation to the study site. The total study duration covers the 90-day post-operative period.

Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone