Actively Recruiting

Phase 2
Age: 18Years - 50Years
FEMALE
NCT06333652

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Led by Mayo Clinic · Updated on 2026-04-28

14

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The researchers are testing a medication named ravulizumab for the treatment of severe preeclampsia and Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP) syndrome.

CONDITIONS

Official Title

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Who Can Participate

Age: 18Years - 50Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals with less than 34 weeks of gestation
  • Individuals with severe preeclampsia or HELLP features
Not Eligible

You will not qualify if you...

  • Pregnant females with disseminated intravascular coagulopathy (DIC)
  • Individuals with non-reassuring fetal status requiring delivery
  • Individuals with non-viable fetuses
  • Pregnancies less than 23 weeks gestation (previable)
  • Individuals with stroke
  • Individuals with in utero fetal demise
  • Known atypical hemolytic uremic syndrome
  • Familial or acquired thrombocytopenia purpura
  • Paroxysmal nocturnal hemoglobinuria
  • Allergy to ravulizumab
  • Inability or unwillingness to sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic Minnesota

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

G

Gonzalez Suarez

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders | DecenTrialz