Actively Recruiting
RCT Glargine vs NPH for Treatment of DM in Pregnancy
Led by Loyola University · Updated on 2024-10-01
160
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
We are asking you to take part in this research study because you are diagnosed with pregestational Type 2 Diabetes Mellitus or Gestational Diabetes Mellitus requiring insulin therapy in pregnancy. Currently, many hospitals differ among use of insulin for management of DM in pregnancy, with NPH, glargine and detemir being the most commonly used forms of basal insulin. Outside of pregnancy, NPH is rarely used with glargine and determir being the more common forms of insulin used due to their fewer episodes of hypoglycemia in these patients. Detemir has been well studied in pregnancy and found to be noninferior to NPH. Unfortunately, glargine has not been as well studied in pregnancy. Thus, with this study we want to compare glargine and NPH. The purpose of this study is to compare two different forms of insulin (Glargine and NPH) that we regularly use to manage diabetes mellitus in pregnancy.
CONDITIONS
Official Title
RCT Glargine vs NPH for Treatment of DM in Pregnancy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient requiring initiation of insulin therapy for Gestational Diabetes Mellitus or Type 2 Diabetes Mellitus in pregnancy
- At least 18 years old
- Insulin started prior to 34 weeks gestation
- Established prenatal care by 14 weeks gestation
You will not qualify if you...
- Under 18 years old
- Unable to consent in English
- Allergy to insulin
- Controlled with diet modification or oral antihyperglycemics only
- Diagnosis of Type 1 Diabetes Mellitus
- Receiving insulin through an insulin pump
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Loyola University Medical Center
Maywood, Illinois, United States, 60153
Actively Recruiting
Research Team
J
Joana Lopes Perdigao, MD
CONTACT
N
Nuong Truong, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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