Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
FEMALE
NCT05526534

A RCT on the Preventive Effect of HFNC on Postoperative Pulmonary Complications in Patients With Gynecologic Neoplasms

Led by Sichuan Cancer Hospital and Research Institute · Updated on 2025-05-23

200

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients at high risk of post-operative pulmonary complications (PPC) will be screened out from gynecological tumor patients undergoing surgical treatment, and randomly assigned into the HFNC group and control group, which uses conventional nasal cannula oxygen therapy. The primary outcome is the incidence of PPC, including postoperative hypoxemia, atelectasis, pneumonia, etc. Secondary outcomes are the improvement of postoperative oxygenation, antibiotic use, length of hospital stay, adverse events related to oxygen therapy, etc.

CONDITIONS

Official Title

A RCT on the Preventive Effect of HFNC on Postoperative Pulmonary Complications in Patients With Gynecologic Neoplasms

Who Can Participate

Age: 18Years - 90Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with gynecologic neoplasms, including benign and malignant tumors, aged 18 to 90 years
  • Scheduled for surgical treatment at the study center
  • Underwent plain chest CT scan within 1 week before surgery
  • Estimated surgical time of 2 hours or more
  • At least one of the following: ARRSPC score of 45 or higher, BMI 30 or more, moderate to severe asthma, moderate to severe COPD, or smoking history of 20 pack-years or more
Not Eligible

You will not qualify if you...

  • Lung metastasis from malignant tumor or primary lung malignant tumor
  • Previous lung surgery or radiotherapy
  • Surgery involving segmental bowel resection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Sichuan Cancer Hospital and Research Institute

Chengdu, Sichuan, China, 610000

Actively Recruiting

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Research Team

D

Dengfeng Wang, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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