Actively Recruiting

Age: 18Years - 69Years
All Genders
NCT05075252

Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?

Led by Niguarda Hospital · Updated on 2026-04-16

1067

Participants Needed

1

Research Sites

417 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Type: prospective observational multicenter trial. Population of interest: adult patients undergoing laparoscopic appendectomy for acute appendicitis. Hypothesis : laparoscopic lavage during laparoscopic appendectomy is a practice that should be used in selected patients according to the intraperitoneal grade of contamination and grade of appendicitis. Nonregulated use of laparoscopic lavage cannot be considered superior to suction only considering recent evidence. Few RCT available addressing this issue are available, but any with a high methodological quality. Aim: The aim of this study is to investigate the impact of laparoscopic lavage during laparoscopic appendectomy on the postoperative incidence of intrabdominal abscesses, stratifying patients in different clusters according to a defined classification considering the intraperitoneal contamination and grade of appendicitis.

CONDITIONS

Official Title

Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?

Who Can Participate

Age: 18Years - 69Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients between 18 and 69 years old
  • Surgical laparoscopic approach for acute appendicitis
  • Intra-operative and histological diagnosis of acute appendicitis
Not Eligible

You will not qualify if you...

  • Patients younger than 18 years old or older than 69 years old
  • Previous appendectomy
  • Previous appendicitis treated without surgery
  • Open surgical approach or conversion from laparoscopic to open surgery
  • Presence of other intra-abdominal infections
  • Immunodeficiency
  • Treatment with steroids, immunosuppressants, or chemotherapy within the past 6 months

AI-Screening

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Trial Site Locations

Total: 1 location

1

ASST GOM Niguarda

Milan, Italy, 20162

Actively Recruiting

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Research Team

S

Stefano Pietro Cioffi, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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