Actively Recruiting
Re-Engaging AYA Survivors in Cancer-Related Healthcare
Led by Children's Hospital of Philadelphia · Updated on 2026-02-18
530
Participants Needed
3
Research Sites
143 weeks
Total Duration
On this page
Sponsors
C
Children's Hospital of Philadelphia
Lead Sponsor
N
Nationwide Children's Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to test the efficacy (how well they work) of different digital interventions that deliver information to adolescent and young adult (AYA) survivors of childhood cancer to promote re-engagement in cancer-related long-term follow-up care (LTFU). The main aims are: * To test the efficacy of adaptive interventions (AIs) that begin with low touch intervention (LTI) as compared to written information (WI) on attending an appointment, and self-reported self-management among AYA. * To identify the most efficacious second-stage strategy for those who initially schedule/attend an appointment (maintenance vs. step-up) and for those who do not (step-up vs. step-up maximum). * To assess multilevel factors contributing to the effects of re-engaging AYA and how best to integrate AIs into practice. Throughout the duration of the study, participants will complete four surveys, receive a series of interventions, and may be asked to participate in an interview (post-intervention).
CONDITIONS
Official Title
Re-Engaging AYA Survivors in Cancer-Related Healthcare
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 15 to 29 years
- History of childhood cancer diagnosed before age 22
- No cancer-related follow-up visit in at least 15 months or 3 months past recommended follow-up
- U.S. resident
- Previously attended a cancer-related appointment at Children's Hospital of Philadelphia, Nationwide Children's Hospital, or Penn
- At least 2 years from end of treatment and 5 years from diagnosis
- Proficient in English
- For participants under 18, a caregiver must provide informed consent
You will not qualify if you...
- Cognitive impairment that limits participation
- Received only surgery as treatment
- Transferred to primary care
- Currently living with cancer diagnosis (new, metastatic, recurrence, or relapse)
- No documentation of treatment history
- Does not meet the inclusion criteria
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Nationwide Children's Hospital
Columbus, Ohio, United States, 43205
Actively Recruiting
2
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
3
Penn Medicine
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
L
Lisa Schwartz, PhD
CONTACT
S
Sara King-Dowling, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
7
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