Actively Recruiting
Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model
Led by Universidad del Desarrollo · Updated on 2024-05-16
24
Participants Needed
1
Research Sites
576 weeks
Total Duration
On this page
Sponsors
U
Universidad del Desarrollo
Lead Sponsor
T
Technical University of Munich
Collaborating Sponsor
AI-Summary
What this Trial Is About
in healthy patients undergoing elective surgery, after a very slow induction, using Eleveld's kinetics as a reference, after loss of consciousness (LOC) and intubation, proceed to infuse propofol until 1% burst suppression ratio is obtained. Then return to the LOC concentration. The BISindex predicted by the model and the real one will be evaluated. The evolution of spectral density frequencies over time will also be evaluated.
CONDITIONS
Official Title
Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model
Who Can Participate
Eligibility Criteria
You may qualify if you...
- ASA I-II patients between 18 and 60 years of age
- Undergoing elective surgery at Hospital Base San José Osorno, Chile
- Consecutive patients admitted within 12 months from study start
You will not qualify if you...
- Emergency surgery patients
- Patients with dementia, delirium, or altered state of consciousness
- Patients with full stomach or risk of aspiration
- Allergy to propofol
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hospital Base san José de Osorno
Osorno, Chile
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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