Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT07264322

Real-Time Dynamic Imaging Study of Normal Pharyngolaryngeal Structures During Barium Swallow (GLAM-III)

Led by Zhejiang Cancer Hospital · Updated on 2025-12-04

3

Participants Needed

1

Research Sites

15 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The integrity and functional stability of pharyngolaryngeal anatomical structures are critical for airway management, and the dynamic changes of key structures (e.g., pyriform sinus, cricoid cartilage lamina) during swallowing directly relate to the design and clinical safety of laryngeal masks. This observational study aims to investigate the real-time dynamic changes and physiological movement patterns of normal pharyngolaryngeal structures during barium swallow using routine barium meal examination imaging. The findings will provide anatomical and physiological evidence for optimizing laryngeal mask design and improving its anatomical fit with the pharynx and larynx.

CONDITIONS

Official Title

Real-Time Dynamic Imaging Study of Normal Pharyngolaryngeal Structures During Barium Swallow (GLAM-III)

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18-75 years
  • No history of pharyngolaryngeal surgery, trauma, or congenital malformation
  • No swallowing dysfunction, pharyngolaryngeal inflammation, or neurological diseases affecting swallowing
  • No recent use of drugs that affect muscle function such as muscle relaxants or anticholinergics
  • Barium meal exam shows an unobstructed oropharyngeal-esophageal pathway
  • Normal pharyngolaryngeal anatomy confirmed by initial imaging
  • Scheduled for routine barium meal examination at Zhejiang Cancer Hospital for diagnosis
Not Eligible

You will not qualify if you...

  • Presence of diseases that may compress pharyngolaryngeal structures such as goiter or mediastinal mass
  • Allergy to barium sulfate or any components of the barium suspension

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Jiangling Wang

Hangzhou, Zhejiang, China, 310022

Actively Recruiting

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Research Team

X

Xiaochun Jin, M.D

CONTACT

J

Jiangling Wang, Ph. D

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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