Actively Recruiting

Phase Not Applicable
Age: 18Years - 55Years
All Genders
NCT05299749

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

Led by Boston VA Research Institute, Inc. · Updated on 2025-09-18

104

Participants Needed

1

Research Sites

226 weeks

Total Duration

On this page

Sponsors

B

Boston VA Research Institute, Inc.

Lead Sponsor

M

Mclean Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Neurofeedback intervention aimed to regulate the superior temporal gyrus (STG) activation and default mode network (DMN) connectivity as well as to reduce the auditory hallucinations (AH) schizophrenia patients with medication resistant AH.

CONDITIONS

Official Title

Real-time fMRI Neurofeedback in Patients With Schizophrenia and Auditory Hallucinations

Who Can Participate

Age: 18Years - 55Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with schizophrenia or schizoaffective disorder using DSM-5 criteria
  • Auditory hallucinations not responsive to medication as confirmed by chart review and clinical interview
Not Eligible

You will not qualify if you...

  • Neurologic illness
  • Major head trauma
  • Electroconvulsive therapy
  • Alcohol or drug dependence
  • Alcohol or drug abuse within the past five years
  • Verbal IQ below 70

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston VA Healthcare System, Brockton

Brockton, Massachusetts, United States, 02301

Actively Recruiting

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Research Team

M

margaret niznikiewicz, PhD

CONTACT

C

Clemens Bauer, phd

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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