Actively Recruiting

Phase Not Applicable
Age: 40Years - 85Years
All Genders
NCT04735627

Real-Time Levodopa Level Monitoring in Parkinson Disease

Led by University of California, San Diego · Updated on 2025-02-11

20

Participants Needed

1

Research Sites

321 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This project aims to develop a minimally invasive sensor device to monitor levodopa levels in real time. We will test the accuracy, tolerability, and safety of this device in people with Parkinson disease.

CONDITIONS

Official Title

Real-Time Levodopa Level Monitoring in Parkinson Disease

Who Can Participate

Age: 40Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Meet the Movement Disorders Society diagnostic criteria for clinically established Parkinson disease
  • Able to provide signed informed consent in English or Spanish
  • Have mild, moderate, or severe Parkinson disease and be able to walk (Hoehn and Yahr stages I-IV)
  • Taking instant release oral carbidopa/levodopa therapy
  • Either not taking or on stable doses of dopamine agonists, MAO-B inhibitors, or COMT inhibitors
Not Eligible

You will not qualify if you...

  • Have other neurological conditions such as stroke, dementia (including Parkinson disease dementia), or traumatic brain injury
  • Have major psychiatric disease
  • Have uncontrolled or active medical conditions like heart, kidney, or liver failure, or diabetes
  • Have had deep brain stimulation (DBS) device placement
  • Have any other condition that investigators believe would place you at risk

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California San DIego

San Diego, California, United States, 92093

Actively Recruiting

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Research Team

M

Michael Skipworth

CONTACT

K

Katherine Longardner, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Real-Time Levodopa Level Monitoring in Parkinson Disease | DecenTrialz