Actively Recruiting
Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions
Led by Brigham and Women's Hospital · Updated on 2026-04-20
1300
Participants Needed
2
Research Sites
245 weeks
Total Duration
On this page
Sponsors
B
Brigham and Women's Hospital
Lead Sponsor
R
RAND
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to predict and minimize post-discharge adverse events (AEs) during care transitions through early identification and escalation of patient-reported symptoms to inpatient and ambulatory clinicians by way of predictive algorithms and clinically integrated digital health apps. We will (1) develop and prospectively validate a predictive model of post-discharge AEs for patients with multiple chronic conditions (MCC); (2) combine, adapt, extend, and iteratively refine our EHR-integrated digital health infrastructure in a series of design sessions with patient and clinician participants; (3) conduct a RCT to evaluate the impact of ePRO monitoring on post-discharge AEs for MCC patients discharged from the general medicine service across Brigham Health; and (4) use mixed methods to evaluate barriers and facilitators of implementation and use as we develop a plan for sustainability, scale, and dissemination.
CONDITIONS
Official Title
Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older
- Hospitalized on the general medicine services at Brigham and Women's Hospital or Brigham and Women's Faulkner Hospital for at least 24 hours
- Planned discharge to home, home with services, or a care facility
- English-speaking patients or those with an English-speaking legally designated healthcare proxy or family caregiver
- Non-English-speaking patients with an English-speaking legally designated healthcare proxy or family caregiver
- Having two or more chronic conditions such as anxiety, asthma, arthritis (osteoarthritis or rheumatoid), atrial fibrillation, cancer, stroke, chronic kidney disease, COPD, cirrhosis, coronary artery or ischemic heart disease, dementia, depression, diabetes mellitus, end-stage renal disease, heart failure, hepatitis B or C, HIV/AIDS, hyperlipidemia, hypertension, inflammatory bowel disease, osteoporosis, sickle cell disease, or substance abuse (alcohol or opioid)
You will not qualify if you...
- Under 18 years of age
- Having fewer than two chronic conditions
- Hospitalized for less than 24 hours
- No identifiable legally designated healthcare proxy or family caregiver
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Brigham and Women's Faulkner Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
2
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
A
Anuj Dalal, MD
CONTACT
S
Savanna Plombon, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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